Ball up your socks and underwear and put them inside your shoes to save room.
Unless you’re going to a remote area with no shops, remember you can purchase your toiletries there. So if you’re struggling for space, consider the option of packing less of the things you can buy relatively cheap at your destination.
If you take medication, ensure you have enough to last you the duration of the trip. Also remember, if your travels are delayed, you may need to take extra. Ensure you follow the rules and regulations regarding carrying particular medications to a different country.
Take copies of your script with you and keep the medication in its box with your name printed on it.
Bring a notebook and pen / pencil. This way you can write down reminders and suggestions from locals (ie: restaurants) and notes about your travel.
Most importantly – don’t forget to pack your sense of adventure!